(Mouse) Bmi1 Antibody (C-term)

日期:2020-08-01 00:36 人气:
Catalog_no AB3333
Product_name (Mouse) Bmi1 Antibody (C-term)
Category 抗原抗体
Reactivity Rat
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN
Specificity This mouse Bmi1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 235-268 amino acids from the C-terminal region of mouse Bmi1.
Dilution WB,1:2000;
othername Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, Bmi1, Bmi-1, Pcgf4
Isotype Rabbit Ig
Background Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity).
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