CASC5 Antibody (C-Term)

日期:2020-08-01 00:36 人气:
Catalog_no AB3374
Product_name CASC5 Antibody (C-Term)
Category 抗原抗体
Reactivity H
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN
Specificity This CASC5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2324-2357 amino acids from human CASC5.
Dilution WB,1:500;
othername Protein CASC5, ALL1-fused gene from chromosome 15q14 protein, AF15q14, Bub-linking kinetochore protein, Blinkin, Cancer susceptibility candidate gene 5 protein, Cancer/testis antigen 29, CT29, Kinetochore-null protein 1, Protein D40/AF15q14, CASC5, KIAA1570, KNL1
Isotype Rabbit Ig
Background Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.
Instructions 查看与下载