SPPL2B Antibody (Center)

日期：2020-08-01 00:36　人气：

Catalog_no	AB3406
Product_name	SPPL2B Antibody (Center)
Category	抗原抗体
Reactivity	H
Size	100μL/50μL
Price	2000.00/1100.00
immunogen	HUMAN
Specificity	This SPPL2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 196-229 amino acids from the Central region of human SPPL2B.
Dilution	WB,1:2000;
othername	Signal peptide peptidase-like 2B, SPP-like 2B, SPPL2b, 3423-, Intramembrane protease 4, IMP-4, Presenilin homologous protein 4, PSH4, Presenilin-like protein 1, SPPL2B, IMP4, KIAA1532, PSL1
Isotype	Rabbit Ig
Background	Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF- alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity.
Instructions	查看与下载