BANP Antibody (N-Term)

日期:2020-08-01 00:36 人气:
Catalog_no AB3558
Product_name BANP Antibody (N-Term)
Category 抗原抗体
Reactivity H
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN
Specificity This BANP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 37-71 amino acids from human BANP.
Dilution WB,1:2000;
othername Protein BANP, BEN domain-containing protein 1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein, BANP, BEND1, SMAR1
Isotype Rabbit Ig
Background Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).
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