SULT2B1 Antibody

日期:2021-06-05 04:40 人气:
Catalog_no AB3763
Product_name SULT2B1 Antibody
Category 抗原抗体
Reactivity H
Size 100μL/50μL
Price 2000.00/1100.00
immunogen HUMAN
Specificity This antibody is generated from a mouse immunized with a reconbinant protein from human.
Dilution WB,1:8000;WB,1:2000;
othername Sulfotransferase family cytosolic 2B member 1, ST2B1, Sulfotransferase 2B1, 2.8.2.2, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, SULT2B1, HSST2
Isotype IgG1,κ
Background Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation (PubMed:28575648).
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