Dovitinib (TKI258, CHIR258)

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0091
Product_name Dovitinib (TKI258, CHIR258)
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 860.00/2660.00/4440.00
Specificity TargetTarget inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively.
Dilution IC50: 5 nM (FGFR3)
Purification 99%
Concentration 靶点:c-Kit;IC50: 5 nM (FGFR3)
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername CHIR-258,CHIR 258
Molecular Weight 392.43
Notes Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively.
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