| Catalog_no |
ADMC0096 |
| Product_name |
XAV-939 |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
660.00/2000.00/3120.00 |
| Specificity |
Target: β-catenin. Fields: XAV-939 selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM, regulates axin levels and does not affect CRE, NF-κB or TGF-β. |
| Dilution |
IC50: 11 nM (TNKS1), 4 nM (TNKS2) |
| Purification |
>98% |
| Concentration |
靶点：β-catenin;IC50： 11 nM (TNKS1), 4 nM (TNKS2) |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| Molecular Weight |
312.31 |
| Notes |
XAV-939 selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM, regulates axin levels and does not affect CRE, NF-κB or TGF-β. |
| Instructions |
 查看与下载 |
