Cobimetinib(GDC-0973; XL518)
日期:2018-09-05 17:14 人气:
Catalog_no | ADMC0143 |
Product_name | Cobimetinib(GDC-0973; XL518) |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 2000.00/5340.00/7340.00 |
Specificity | Target: MEK. Fields: GDC-0973 is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase, also known as MEK, a serine/threonine kinase that is a component of the RAS/RAF/MEK/ERK pathway. IC50: 4.2 nM (MEK1) |
Dilution | IC50: 4.2 nM (MEK1) |
Purification | purity:>98% |
Concentration | 靶点:MEK;IC50: 4.2 nM (MEK1) |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | xl-518,GDC 0973 (XL518),Cobimetinib,GDC0973,XL-518,XL 518,GDC 0973 |
Molecular Weight | 531.31 |
Notes | GDC-0973 is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase, also known as MEK, a serine/threonine kinase that is a component of the RAS/RAF/MEK/ERK pathway. IC50: 4.2 nM (MEK1) |
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