Ruxolitinib (INCB018424)
日期:2018-09-05 17:14 人气:
Catalog_no | ADMC0150 |
Product_name | Ruxolitinib (INCB018424) |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 780.00/1340.00/1780.00 |
Specificity | Target: JAK. Fields: Ruxolitinib is a potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5 nM, respectively and is relatively less selective for JAK3 (IC50 = 322 nM). |
Dilution | IC50: 3.3 nM (JAK1), 2.8 nM (JAK2) |
Purification | 99% |
Concentration | 靶点:JAK;IC50: 3.3 nM (JAK1), 2.8 nM (JAK2) |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | Ruxolitinib |
Molecular Weight | 306.371 |
Notes | Ruxolitinib is a potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5 nM, respectively and is relatively less selective for JAK3 (IC50 = 322 nM). |
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