NVP-BEZ235

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0154
Product_name NVP-BEZ235
Category 抑制剂与激动剂
Size 50mg/100mg
Price 560.00/880.00
Specificity Target: PI3K. Fields: BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM.
Dilution IC50: 4 nM (p110α), 5 nM (p110γ), 7 nM (p110δ), 75 nM (p110β), 6 nM (mTOR)[1]
Purification >98%
Concentration 靶点:PI3K;IC50: 4 nM (p110α), 5 nM (p110γ), 7 nM (p110δ), 75 nM (p110β), 6 nM (mTOR)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername BEZ235
Molecular Weight 469.55
Notes BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM.
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