| Catalog_no |
ADMC0161 |
| Product_name |
Pazopanib |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
560.00/1120.00/1660.00 |
| Specificity |
TargetTargeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit. IC50: 10 nM (VEGFR1), 30 nM (VEGFR2), 47 nM (VEGFR3), 74 nM (c-Kit), 84 nM (PDGFRβ), 140 nM (FGFR1), 146 nM (c-Fms)[1] |
| Dilution |
IC50: 10 nM (VEGFR1), 30 nM (VEGFR2), 47 nM (VEGFR3), 74 nM (c-Kit), 84 nM (PDGFRβ), 140 nM (FGFR1), 146 nM (c-Fms)[1] |
| Purification |
99% |
| Concentration |
靶点：VEGFR;IC50： 10 nM (VEGFR1), 30 nM (VEGFR2), 47 nM (VEGFR3), 74 nM (c-Kit), 84 nM (PDGFRβ), 140 nM (FGFR1), 146 nM (c-Fms)[1] |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
Votrient |
| Molecular Weight |
437.52 |
| Notes |
Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit. IC50: 10 nM (VEGFR1), 30 nM (VEGFR2), 47 nM (VEGFR3), 74 nM (c-Kit), 84 nM (PDGFRβ), 140 nM (FGFR1), 146 nM (c-Fms) |
| Instructions |
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