| Catalog_no |
ADMC0211 |
| Product_name |
AZD1080 |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
3880.00/9500.00/14780.00 |
| Specificity |
Target: GSK-3. Fields: AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows >14-fold selectivity against CDK2, CDK5, CDK1 and Erk2. IC50: 6.9 nM (GSK3α |
| Dilution |
IC50: 6.9 nM (GSK3α), 31 nM (GSK3β)[1]pKi: 8.2 (GSK3α), 7.5 (GSK3β)[1] |
| Purification |
>98% |
| Concentration |
靶点：GSK-3;IC50： 6.9 nM (GSK3α), 31 nM (GSK3β)[1]pKi: 8.2 (GSK3α), 7.5 (GSK3β)[1] |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
AZD 1080,AZD-1080 |
| Molecular Weight |
334.37 |
| Notes |
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows >14-fold selectivity against CDK2, CDK5, CDK1 and Erk2. IC50: 6.9 nM (GSK3α), 31 nM (GSK3β)[1]pKi: |
| Instructions |
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