Baricitinib (INCB28050, LY3009104)

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0222
Product_name Baricitinib (INCB28050, LY3009104)
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 780.00/1340.00/1660.00
Specificity Target: JAK. Fields: Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Phase 3.
Dilution IC50: 5.9 nM (JAK1), 5.7 nM (JAK2), >400 (JAK3), 53 nM (Tyk2)[1]
Purification >98%
Concentration 靶点:JAK;IC50: 5.9 nM (JAK1), 5.7 nM (JAK2), >400 (JAK3), 53 nM (Tyk2)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername Baricitinib, INCB28050, LY3009104.
Molecular Weight 371.4
Notes Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Phase 3.
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