Luminespib (NVP-AUY922)

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0267
Product_name Luminespib (NVP-AUY922)
Category 抑制剂与激动剂
Size 10mg/100mg
Price 780.00/3880.00
Specificity Target: HSP. Fields: AUY922 (NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. P
Dilution IC50: 13 nM (HSP90α), 21 nM (HSP90β)
Purification 99.13%
Concentration 靶点:HSP;IC50: 13 nM (HSP90α), 21 nM (HSP90β)
Storage_stability 2 years -20°C powder,2 weeks 4°C in DMSO,6 months -80°C in DMSO
othername AUY 922,AUY-922, NVP-AUY922,NVP-AUY922-NX,AUY922,VER-52296
Molecular Weight 465.54
Notes AUY922 (NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 1/2.
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