| Catalog_no |
ADMC0271 |
| Product_name |
BKM120 (NVP-BKM120, Buparlisib) |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
1000.00/1340.00/1660.00 |
| Specificity |
Target: PI3K. Fields: BKM120 is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. |
| Dilution |
IC50: 52 nM (p110α), 166 nM (p110β), 116 nM (p110δ), 262 nM (p110γ)[1] |
| Purification |
>98% |
| Concentration |
靶点：PI3K;IC50： 52 nM (p110α), 166 nM (p110β), 116 nM (p110δ), 262 nM (p110γ)[1] |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
NVP-BKM-120, BKM-120; Buparlisib |
| Molecular Weight |
410.39 |
| Notes |
BKM120 is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. |
| Instructions |
 查看与下载 |
