Mereletinib(AZD-9291,Osimertinib)

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0283
Product_name Mereletinib(AZD-9291,Osimertinib)
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 780.00/1340.00/1660.00
Specificity Target: EGFR. Fields: AZD-9291 is a potent and selective mutated forms EGFR inhibitor(Exon 19 deletion EGFR IC50=12.92 nM, L858R/T790M EGFR IC50= 11.44 nM, wild type EGFR IC50= 493.8 nM).
Dilution IC50: 1 nM (EGFRL858R/T790M), 12 nM (EGFRL858R)[1]
Purification >98%
Concentration 靶点:EGFR;IC50: 1 nM (EGFRL858R/T790M), 12 nM (EGFRL858R)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername EGFR inhibitor; AZD9291; AZD 9291,Tagrisso
Molecular Weight 499.61
Notes AZD-9291 is a potent and selective mutated forms EGFR inhibitor(Exon 19 deletion EGFR IC50=12.92 nM, L858R/T790M EGFR IC50= 11.44 nM, wild type EGFR IC50= 493.8 nM).
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