| Catalog_no |
ADMC0313 |
| Product_name |
Bi 2536 |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
2200.00/5860.00/9520.00 |
| Specificity |
Target: Polo-like Kinase (PLK). Fields: BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM). |
| Dilution |
IC50: 0.83 nM (Plk1), 3.5 nM (Plk2/Snk), 9 nM (Plk3/Fnk)[1]IC50: 25 nM (BRD4)[2] |
| Purification |
>98% |
| Concentration |
靶点：Polo-like Kinase (PLK);IC50： 0.83 nM (Plk1), 3.5 nM (Plk2/Snk), 9 nM (Plk3/Fnk)[1] 25 nM (BRD4)[2] |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
BI-2536; BI2536 |
| Molecular Weight |
521.66 |
| Notes |
BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM). |
| Instructions |
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