Nintedanib (BIBF 1120)
日期:2018-09-05 17:14 人气:
Catalog_no | ADMC0314 |
Product_name | Nintedanib (BIBF 1120) |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 620.00/1060.00/1340.00 |
Specificity | Target: PDGFR. Fields: Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. |
Dilution | IC50: 34 nM (VEGFR1), 13 nM (VEGFR2), 13 nM (VEGFR3), 69 nM (FGFR1), 37 nM (FGFR1), 108 nM (FGFR1), 59 nM (PDGFRα), 65 nM (PDGFRβ) |
Purification | 99.50% |
Concentration | 靶点:PDGFR;IC50: 34 nM (VEGFR1), 13 nM (VEGFR2), 13 nM (VEGFR3), 69 nM (FGFR1), 37 nM (FGFR1), 108 nM (FGFR1), 59 nM (PDGFRα), 65 nM (PDGFRβ) |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | Nintedanib; BIBF1120; Vargatef; BIBF-1120 |
Molecular Weight | 539.62 |
Notes | Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. |
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