Rociletinib (CO-1686)

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0326
Product_name Rociletinib (CO-1686)
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 880.00/1840.00/2840.00
Specificity TargetTargets the mutant forms of EGFR including T790M(IC50=21 nM).
Dilution IC50: 21.5 nM (EGFRL858R/T790M), 303.3 nM (EGFRWT)
Purification >99%
Concentration 靶点:EGFR;IC50: 21.5 nM (EGFRL858R/T790M), 303.3 nM (EGFRWT)
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername Rociletinib, AVL-301; CNX-419,co 1686,co1686
Molecular Weight 555.55
Notes CO-1686 is a novel, irreversible and orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M(IC50=21 nM).
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