Quisinostat (JNJ-26481585) 2HCl

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0366
Product_name Quisinostat (JNJ-26481585) 2HCl
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 2340.00/4660.00/6880.00
Specificity Target: HDAC. Fields: Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity aga
Dilution IC50: 0.11 nM (HDAC1), 0.33 nM (HDAC2), 0.64 nM (HDAC4), 0.46 nM (HDAC10), 0.37 nM (HDAC11)[1]
Purification >98%
Concentration 靶点:HDAC;IC50: 0.11 nM (HDAC1), 0.33 nM (HDAC2), 0.64 nM (HDAC4), 0.46 nM (HDAC10), 0.37 nM (HDAC11)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername JNJ26481585,JNJ 26481585
Molecular Weight 467.39
Notes Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and
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