LCL-161

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0376
Product_name LCL-161
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 1780.00/5560.00/8220.00
Specificity Target: IAP. Fields: LCL161 is an oral small molecule antagonist of Apoptosis Proteins (IAPs) that sensitizes a subset of tumors from diverse lineages to treatment with cytotoxic therapies. IC50: 35 nM (XIAP, in HEK293 cell), 0.40 nM (cIAP1, in MDA-
Dilution IC50: 35 nM (XIAP, in HEK293 cell), 0.40 nM (cIAP1, in MDA-MB-231)[1]
Purification >98%
Concentration 靶点:IAP;IC50: 35 nM (XIAP, in HEK293 cell), 0.40 nM (cIAP1, in MDA-MB-231)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername LCL-161; LCL161
Molecular Weight 500.63
Notes LCL161 is an oral small molecule antagonist of Apoptosis Proteins (IAPs) that sensitizes a subset of tumors from diverse lineages to treatment with cytotoxic therapies. IC50: 35 nM (XIAP, in HEK293 cell), 0.40 nM (cIAP1, in MDA-MB-231)[1]
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