| Catalog_no |
ADMC0440 |
| Product_name |
TG101209 |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
1500.00/4500.00/8340.00 |
| Specificity |
Target: FLT3. Fields: TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations; TG101209 inhibit BRD4 a |
| Dilution |
IC50: 6 nM (JAK2), 25 nM (Flt3), 17 nM (RET), 130 nM (BRD4) |
| Purification |
>98% |
| Concentration |
靶点：FLT3;IC50： 6 nM (JAK2), 25 nM (Flt3), 17 nM (RET), 130 nM (BRD4) |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
TG 101209; TG-101209 |
| Molecular Weight |
509.67 |
| Notes |
TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations; TG101209 inhibit BRD4 activity with IC50 of 13 |
| Instructions |
 查看与下载 |
