DAPT

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0483
Product_name DAPT
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 1060.00/3280.00/5920.00
Specificity Target: γ-secretase. Fields: DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, ce
Dilution IC50: 20 nM (Aβ, in HEK 293 cells)[1]
Purification >98%
Concentration 靶点:γ-secretase;IC50: 20 nM (Aβ, in HEK 293 cells)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername GSI-IX; GSI IX
Molecular Weight 432.46
Notes DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma.
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