Taselisib(GDC-0032)

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0493
Product_name Taselisib(GDC-0032)
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 1340.00/3340.00/5340.00
Specificity TargetTargeting PI3Kα/δ/γ with IC50 of 0.29 nM/0.12 nM/0.97nM, >10 fold selective over PI3Kβ.
Dilution IC50: 0.29 nM (PI3Kα), 0.91 nM (PI3Kβ), 0.97 nM (PI3Kγ), 0.12 nM (PI3Kδ)
Purification >98%
Concentration 靶点:PI3K;IC50: 0.29 nM (PI3Kα), 0.91 nM (PI3Kβ), 0.97 nM (PI3Kγ), 0.12 nM (PI3Kδ)
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername GDC0032; GDC 0032,RG7604
Molecular Weight 460.53
Notes GDC-0032 is a potent, next-generation β isoform-sparing PI3K inhibitor targeting PI3Kα/δ/γ with IC50 of 0.29 nM/0.12 nM/0.97nM, >10 fold selective over PI3Kβ.
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