Ribociclib (LEE011)
日期:2018-09-05 17:14 人气:
Catalog_no | ADMC0508 |
Product_name | Ribociclib (LEE011) |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 880.00/1340.00/2000.00 |
Specificity | TargetTargeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. IC50: 10/39 nM (CDK4/6)[1] |
Dilution | IC50: 10/39 nM (CDK4/6)[1] |
Purification | >99% |
Concentration | 靶点:CDK;IC50: 10/39 nM (CDK4/6)[1] |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | LEE 011; LEE-011,Ribociclib,LEE011 |
Molecular Weight | 434.54 |
Notes | LEE011 is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. IC50: 10/39 nM (CDK4/6)[1] |
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