Torkinib (PP242)
日期:2018-09-05 17:14 人气:
Catalog_no | ADMC0523 |
Product_name | Torkinib (PP242) |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 820.00/1960.00/3520.00 |
Specificity | TargetTargets both mTOR complexes with >10- and 100-fold selectivity for mTOR than PI3Kδ or PI3Kα/β/γ, respectively; also showed slightly weaker activity against BRD4 (Kd= 1.7 uM). |
Dilution | IC50: 8 nM (mTOR), 100 nM (p110δ), 410 nM (DNA-PK), 410 nM (PDGFR)[1] |
Purification | >98% |
Concentration | 靶点:mTOR;IC50: 8 nM (mTOR), 100 nM (p110δ), 410 nM (DNA-PK), 410 nM (PDGFR)[1] |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | TORKinib,PP242; PP-242,PP 242 |
Molecular Weight | 308.34 |
Notes | PP242 is a selective mTOR inhibitor with IC50 of 8 nM; targets both mTOR complexes with >10- and 100-fold selectivity for mTOR than PI3Kδ or PI3Kα/β/γ, respectively; also showed slightly weaker activity against BRD4 (Kd= 1.7 uM). |
Instructions | 查看与下载 |
- 产品详情
- 发表文献
- 用户反馈
- 相关产品
- 在线问答