| Catalog_no |
ADMC0537 |
| Product_name |
VE-822 |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
1140.00/3640.00/6120.00 |
| Specificity |
Target: ATM/ATR . Fields: VE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM). Ki: <0.2 nM (ATR), 34 nM (ATM)[1]
IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cel |
| Dilution |
Ki: <0.2 nM (ATR), 34 nM (ATM)[1]
IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 and MiaPaCa-2 cells)[1]
|
| Purification |
>98% |
| Concentration |
靶点：ATM/ATR;IC50：Ki: <0.2 nM (ATR), 34 nM (ATM)[1]
19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 and MiaPaCa-2 cells)[1]
|
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
VE822; VE 822 |
| Molecular Weight |
463.55 |
| Notes |
VE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM). Ki: <0.2 nM (ATR), 34 nM (ATM)[1]
IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 |
| Instructions |
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