Evofosfamide(TH-302)
日期:2018-09-05 17:14 人气:
Catalog_no | ADMC0616 |
Product_name | Evofosfamide(TH-302) |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 3120.00/8660.00/13560.00 |
Specificity | TargetTargeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism. |
Dilution | Hypoxia-activated prodrug[1] |
Purification | >98% |
Concentration | 靶点:See reference;IC50:Hypoxia-activated prodrug[1] |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | TH 302; TH302 |
Molecular Weight | 449.04 |
Notes | TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism. |
Instructions | 查看与下载 |
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