URMC-099

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0696
Product_name URMC-099
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 1660.00/5000.00/9000.00
Specificity Target: Mixed Lineage Kinase. Fields: URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity
Purification >98%
Concentration 靶点:Mixed Lineage Kinase;IC50:No data
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername URMC-099,URMC 099
Molecular Weight 421.54
Notes URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM.
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