PF06463922(Lorlatinib)

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0709
Product_name PF06463922(Lorlatinib)
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 1000.00/2660.00/4660.00
Specificity Target: ALK. Fields: PF06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity. Ki: < 0.02 nM (ROS1), < 0.07 nM
Dilution Ki: < 0.02 nM (ROS1), < 0.07 nM (ALK WT), 0.7 nM (ALK L1196M)
Purification >99%
Concentration 靶点:ALK;IC50:Ki: < 0.02 nM (ROS1), < 0.07 nM (ALK WT), 0.7 nM (ALK L1196M)
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername PF06463922,PF-06463922,PF 06463922
Molecular Weight 406.1
Notes PF06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity. Ki: < 0.02 nM (ROS1), < 0.07 nM (ALK WT), 0.7 nM (ALK
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