| Catalog_no |
ADMC0875 |
| Product_name |
Entrectinib (RXDX-101) |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
1340.00/5000.00/8220.00 |
| Specificity |
Target: ALK. Fields: Entrectinib (RXDX-101), a potent and selective small molecule inhibitor of TrkA/B/C, ROS1, and ALK kinases, has demonstrated early clinical activity when orally administered intermittently under fasting conditions. IC50: 1 nM (Tr |
| Dilution |
IC50: 1 nM (TrkA), 1 nM (TrkB), 1 nM (TrkC), 1 nM (ROS1),1 nM (ALK)[1] |
| Purification |
>98% |
| Concentration |
靶点：ALK;IC50： 1 nM (TrkA), 1 nM (TrkB), 1 nM (TrkC), 1 nM (ROS1),1 nM (ALK)[1] |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
NMS E628; RXDX-101,NMSE628; RXDX 101,NMS-E628; RXDX101 |
| Molecular Weight |
560.64 |
| Notes |
Entrectinib (RXDX-101), a potent and selective small molecule inhibitor of TrkA/B/C, ROS1, and ALK kinases, has demonstrated early clinical activity when orally administered intermittently under fasting conditions. IC50: 1 nM (TrkA), 1 nM (TrkB), 1 n |
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