| Catalog_no |
ADMC0928 |
| Product_name |
BI-847325 |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
2000.00/7000.00/9780.00 |
| Specificity |
Target: MEK. Fields: BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respec |
| Dilution |
IC50: 25 nM (hAK-A), 15 nM (hAK-C), 25 nM (MEK1), 4 nM (MEK2)[1] |
| Purification |
>98% |
| Concentration |
靶点：MEK;IC50： 25 nM (hAK-A), 15 nM (hAK-C), 25 nM (MEK1), 4 nM (MEK2)[1] |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
BI-847325,BI 847325,BI847325 |
| Molecular Weight |
464.56 |
| Notes |
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1. |
| Instructions |
 查看与下载 |
