| Catalog_no |
ADMC0954 |
| Product_name |
MK-2461 |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
3880.00/13340.00/24000.00 |
| Specificity |
TargetTargetTargets versus FGFR1, FGFR2, FGFR3, PDGFRβ, KDR, Flt3, Flt4, TrkA, and TrkB. |
| Purification |
>98% |
| Concentration |
靶点：c-Met/HGFR;IC50：No data |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
MK-2461,MK2461,MK 2461 |
| Molecular Weight |
495.55 |
| Notes |
MK-2461 is a potent, multi-targeted inhibitor for c-Met(WT/mutants) with IC50 of 0.4-2.5 nM, less potent to Ron, Flt1; 8- to 30-fold greater selectivity of c-Met targets versus FGFR1, FGFR2, FGFR3, PDGFRβ, KDR, Flt3, Flt4, TrkA, and TrkB. |
| Instructions |
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