NVP-LDE225(Erismodegib)

日期:2018-09-05 17:14 人气:
Catalog_no ADMC0962
Product_name NVP-LDE225(Erismodegib)
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 780.00/1660.00/2780.00
Specificity Target: Smo . Fields: LDE225 (NVP-LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively. Phase 3.
Dilution IC50: 1.3 nM (mSmo), 2.5 nM (hSmo)[1]
Purification >98%
Concentration 靶点:Smo;IC50: 1.3 nM (mSmo), 2.5 nM (hSmo)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername NVP-LDE225,LDE225
Molecular Weight 485.5
Notes LDE225 (NVP-LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively. Phase 3.
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