| Catalog_no |
ADMC0979 |
| Product_name |
GDC-0152 |
| Category |
抑制剂与激动剂 |
| Size |
10mg/50mg/100mg |
| Price |
1840.00/6340.00/11400.00 |
| Specificity |
Target: IAP. Fields: GDC-0152 is a potent inhibitor of IAPs; binds to the XIAP BIR3 domain, the BIR domain of ML-IAP, and the BIR3 domains of cIAP1 and cIAP2 with K(i) values of 28, 14, 17, and 43 nM, respectively. Ki: 28 nM (XIAP BIR3), 14 nM (MLIAP |
| Dilution |
Ki: 28 nM (XIAP BIR3), 14 nM (MLIAP-BIR3), 17 nM (cIAP1-BIR3), 43 nM (cIAP2-BIR3) |
| Purification |
>98% |
| Concentration |
靶点：IAP;IC50：Ki: 28 nM (XIAP BIR3), 14 nM (MLIAP-BIR3), 17 nM (cIAP1-BIR3), 43 nM (cIAP2-BIR3) |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
GDC-0152; GDC0152; GDC 0152. |
| Molecular Weight |
498.64 |
| Notes |
GDC-0152 is a potent inhibitor of IAPs; binds to the XIAP BIR3 domain, the BIR domain of ML-IAP, and the BIR3 domains of cIAP1 and cIAP2 with K(i) values of 28, 14, 17, and 43 nM, respectively. Ki: 28 nM (XIAP BIR3), 14 nM (MLIAP-BIR3), 17 nM (cIAP1- |
| Instructions |
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