| Catalog_no |
ADMC1026 |
| Product_name |
NVP-BEZ235 Tosylate |
| Category |
抑制剂与激动剂 |
| Size |
50mg/100mg |
| Price |
660.00/1000.00 |
| Specificity |
Target: mTOR . Fields: BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM. |
| Dilution |
IC50: 4nM (PI3Kα), 75 nM (PI3Kβ), 7 nM (PI3Kγ), 5 nM (PI3Kδ)[1] |
| Purification |
>98% |
| Concentration |
靶点：mTOR;IC50： 4nM (PI3Kα), 75 nM (PI3Kβ), 7 nM (PI3Kγ), 5 nM (PI3Kδ)[1] |
| Storage_stability |
2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername |
BEZ235 |
| Molecular Weight |
641.74 |
| Notes |
BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM. |
| Instructions |
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