CWHM-12

日期:2018-09-05 17:14 人气:
Catalog_no ADMC1099
Product_name CWHM-12
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 5560.00/16660.00/23340.00
Specificity Target: Integrin. Fields: CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1.
Dilution IC50: 0.2 nM (αvβ8), 0.8 nM (αvβ3), 1.5 nM (αvβ6), 1.8 nM (αvβ1), 61 nM (αvβ5)[1]
Purification >98%
Concentration 靶点:Integrin;IC50: 0.2 nM (αvβ8), 0.8 nM (αvβ3), 1.5 nM (αvβ6), 1.8 nM (αvβ1), 61 nM (αvβ5)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername CWHM 12,CWHM12
Molecular Weight 590.47
Notes CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1.
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