Niraparib(MK-4827) tosylate

日期:2018-09-05 17:14 人气:
Catalog_no ADMC1126
Product_name Niraparib(MK-4827) tosylate
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 1660.00/4440.00/7220.00
Specificity Target: PARP. Fields: MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.
Dilution IC50: 3.8 nM (PARP1), 2.1 nM (PARP2)[1]
Purification >98%
Concentration 靶点:PARP;IC50: 3.8 nM (PARP1), 2.1 nM (PARP2)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername Niraparib tosylate;MK 4827 tosylate;MK4827 tosylate
Molecular Weight 492.5899
Notes MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.
Instructions 查看与下载


  • 产品详情
  • 发表文献
  • 用户反馈
  • 相关产品
  • 在线问答