LEE011 hydrochloride

日期:2018-09-05 17:14 人气:
Catalog_no ADMC1203
Product_name LEE011 hydrochloride
Category 抑制剂与激动剂
Size 10mg/50mg/100mg
Price 880.00/1660.00/2780.00
Specificity TargetTargeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. IC50: 10/39 nM (CDK4/6)[1]
Dilution IC50: 10/39 nM (CDK4/6)[1]
Purification >98%
Concentration 靶点:CDK;IC50: 10/39 nM (CDK4/6)[1]
Storage_stability 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othername Ribociclib; LEE 011; LEE-011
Molecular Weight 471.0
Notes LEE011 Hcl is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. IC50: 10/39 nM (CDK4/6)[1]
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