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| Catalog_no | ADMC0057 |
| Product_name | Regorafenib (BAY73-4506,Fluoro-Sorafenib) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 720.00/1060.00/1620.00 |
| Specificity | TargetTarget inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. |
| Dilution | IC50: 13 nM (VEGFR1), 4.2 nM (VEGFR2), 46 nM (VEGFR3), 22 nM (PDGFRβ), 7 nM (Kit), 1.5 nM (RET), 2.5 nM (Raf-1) |
| Purification | >98% |
| Concentration | 靶点：VEGFR;IC50： 13 nM (VEGFR1), 4.2 nM (VEGFR2), 46 nM (VEGFR3), 22 nM (PDGFRβ), 7 nM (Kit), 1.5 nM (RET), 2.5 nM (Raf-1) |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | Regorafenib, BAY 73-4506, Sorafenib, BAY-73-4506, BAY 73 4506 |
| Observed_band | 482.82 |
| Notes | Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. |
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