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| Catalog_no | ADMC0075 |
| Product_name | XL-184 (Cabozantinib,BMS907351) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 840.00/1100.00/1620.00 |
| Specificity | Target: VEGFR . Fields: XL184 (Cabozantinib) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. |
| Dilution | IC50: 0.035 nM (VEGFR2), 1.3 nM (c-Met), 4.6 nM (Kit), 7 nM (Axl), 11.3 nM (Flt3)[1] |
| Purification | >98% |
| Concentration | 靶点：VEGFR;IC50： 0.035 nM (VEGFR2), 1.3 nM (c-Met), 4.6 nM (Kit), 7 nM (Axl), 11.3 nM (Flt3)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | XL184, Cabozantinib, BMS907351, BMS-907351, BMS 907351 |
| Observed_band | 501.51 |
| Notes | XL184 (Cabozantinib) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. |
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