| Catalog_no | ADMC0143 |
| Product_name | Cobimetinib(GDC-0973; XL518) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 2000.00/5340.00/7340.00 |
| Specificity | Target: MEK. Fields: GDC-0973 is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase, also known as MEK, a serine/threonine kinase that is a component of the RAS/RAF/MEK/ERK pathway. IC50: 4.2 nM (MEK1) |
| Dilution | IC50: 4.2 nM (MEK1) |
| Purification | purity:>98% |
| Concentration | 靶点：MEK;IC50： 4.2 nM (MEK1) |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | xl-518,GDC 0973 (XL518),Cobimetinib,GDC0973,XL-518,XL 518,GDC 0973 |
| Observed_band | 531.31 |
| Notes | GDC-0973 is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase, also known as MEK, a serine/threonine kinase that is a component of the RAS/RAF/MEK/ERK pathway. IC50: 4.2 nM (MEK1) |
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