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| Catalog_no | ADMC0156 |
| Product_name | Apitolisib(GDC-0980) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1440.00/4220.00/7220.00 |
| Specificity | Target: PI3K . Fields: GDC-0980 (RG7422) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM, respectively. Also a mTOR inhibitor with Ki of 17 nM, and highly selective versus others PIKK family kinases. |
| Dilution | IC50: 5 nM (PI3Kα), 27 nM (PI3Kβ), 7 nM (PI3Kδ), 14 nM (PI3Kγ) |
| Purification | >98% |
| Concentration | 靶点：PI3K;IC50： 5 nM (PI3Kα), 27 nM (PI3Kβ), 7 nM (PI3Kδ), 14 nM (PI3Kγ) |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | GDC-0980; RG7422; RG-7422; GDC 0980; GNE 390. |
| Observed_band | 498.6 |
| Notes | GDC-0980 (RG7422) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM, respectively. Also a mTOR inhibitor with Ki of 17 nM, and highly selective versus others PIKK family kinases. |
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