400-921-8278
| Catalog_no | ADMC0161 |
| Product_name | Pazopanib |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 560.00/1120.00/1660.00 |
| Specificity | TargetTargeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit. IC50: 10 nM (VEGFR1), 30 nM (VEGFR2), 47 nM (VEGFR3), 74 nM (c-Kit), 84 nM (PDGFRβ), 140 nM (FGFR1), 146 nM (c-Fms)[1] |
| Dilution | IC50: 10 nM (VEGFR1), 30 nM (VEGFR2), 47 nM (VEGFR3), 74 nM (c-Kit), 84 nM (PDGFRβ), 140 nM (FGFR1), 146 nM (c-Fms)[1] |
| Purification | 99% |
| Concentration | 靶点：VEGFR;IC50： 10 nM (VEGFR1), 30 nM (VEGFR2), 47 nM (VEGFR3), 74 nM (c-Kit), 84 nM (PDGFRβ), 140 nM (FGFR1), 146 nM (c-Fms)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | Votrient |
| Observed_band | 437.52 |
| Notes | Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit. IC50: 10 nM (VEGFR1), 30 nM (VEGFR2), 47 nM (VEGFR3), 74 nM (c-Kit), 84 nM (PDGFRβ), 140 nM (FGFR1), 146 nM (c-Fms) |
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