400-921-8278
| Catalog_no | ADMC0166 |
| Product_name | Compound 401 |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1440.00/5120.00/9440.00 |
| Specificity | Target: DNA-PK. Fields: Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over FRAP (mTOR) (IC50 = 5.3 µM). |
| Dilution | |
| Purification | >98% |
| Concentration | 靶点：DNA-PK;IC50：No data |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | Compound401,Compound-401 |
| Observed_band | 281.314 |
| Notes | Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over FRAP (mTOR) (IC50 = 5.3 µM). |
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