抑制剂与激动剂

Catalog_noADMC0225
Product_nameIdelalisib (CAL-101,GS-1101)
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price720.00/1440.00/1660.00
SpecificityTarget: PI3K . Fields: CAL-101 is a selective p110δ inhibitor with IC50 of 2.5 nM; shown to have 40- to 300-fold greater selectivity for p110δ thanp110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.
DilutionIC50: 2.5 nM (p110δ), 89 nM (p110γ), 565 nM (p110β), 820 nM (p110α)[1]
Purification>99.5%,ee purity>99%
Concentration靶点:PI3K;IC50: 2.5 nM (p110δ), 89 nM (p110γ), 565 nM (p110β), 820 nM (p110α)[1]
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameIdelalisib; CAL-101, GS-1101; GS 1101; GS1101,CAL101
Observed_band415.423
NotesCAL-101 is a selective p110δ inhibitor with IC50 of 2.5 nM; shown to have 40- to 300-fold greater selectivity for p110δ thanp110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.
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