抑制剂与激动剂

Catalog_noADMC0227
Product_nameIOX2
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price1000.00/3880.00/7000.00
SpecificityTarget: HIF/HIF Prolyl-Hydroxylase. Fields: IOX 2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). IOX 2 displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases.
DilutionIC50: 22 nM (PHD2)[1]
Purification>98%
Concentration靶点:HIF/HIF Prolyl-Hydroxylase;IC50: 22 nM (PHD2)[1]
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameIOX-2; IOX2; IOX 2
Observed_band352.34
NotesIOX 2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). IOX 2 displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases.
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