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| Catalog_no | ADMC0240 |
| Product_name | Dabrafenib (GSK2118436) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 780.00/1660.00/2660.00 |
| Specificity | Target: Raf. Fields: Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. Phase 3. |
| Dilution | IC50: 0.6 nM (BRAFV600E), 5 nM (CRAF)[4] |
| Purification | >98% |
| Concentration | 靶点：Raf;IC50： 0.6 nM (BRAFV600E), 5 nM (CRAF)[4] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | GSK2118436A (Dabrafenib). GSK-2118436B (Dabrafenib Mesylate) |
| Observed_band | 519.56 |
| Notes | Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. Phase 3. |
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