抑制剂与激动剂

Catalog_noADMC0240
Product_nameDabrafenib (GSK2118436)
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price780.00/1660.00/2660.00
SpecificityTarget: Raf. Fields: Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. Phase 3.
DilutionIC50: 0.6 nM (BRAFV600E), 5 nM (CRAF)[4]
Purification>98%
Concentration靶点:Raf;IC50: 0.6 nM (BRAFV600E), 5 nM (CRAF)[4]
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameGSK2118436A (Dabrafenib). GSK-2118436B (Dabrafenib Mesylate)
Observed_band519.56
NotesDabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. Phase 3.
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