| Catalog_no | ADMC0249 |
| Product_name | NVP-BGJ398(Infigratinib) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 780.00/1560.00/2660.00 |
| Specificity | Target: FGFR. Fields: BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2. |
| Dilution | IC50: 0.9 nM (FGFR1), 1.4 nM (FGFR2), 1 nM (FGFR3), 60 nM (FGFR4)[1] |
| Purification | >98% |
| Concentration | 靶点：FGFR;IC50： 0.9 nM (FGFR1), 1.4 nM (FGFR2), 1 nM (FGFR3), 60 nM (FGFR4)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | NVP-BGJ398, BGJ398, BGJ-398,Infigratinib,BGJ 398 |
| Observed_band | 560.47 |
| Notes | BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2. |
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