抑制剂与激动剂

Catalog_noADMC0267
Product_nameLuminespib (NVP-AUY922)
Category抑制剂与激动剂
Size10mg/100mg
Price780.00/3880.00
SpecificityTarget: HSP. Fields: AUY922 (NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. P
DilutionIC50: 13 nM (HSP90α), 21 nM (HSP90β)
Purification99.13%
Concentration靶点:HSP;IC50: 13 nM (HSP90α), 21 nM (HSP90β)
Storage_stability2 years -20°C powder,2 weeks 4°C in DMSO,6 months -80°C in DMSO
othernameAUY 922,AUY-922, NVP-AUY922,NVP-AUY922-NX,AUY922,VER-52296
Observed_band465.54
NotesAUY922 (NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 1/2.
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